Advanced technology: clinical blessing or clinical blinders?

نویسنده

  • Robert J Hall
چکیده

Clinical Blinders? To the Editor: In their article “Occult anomalous pulmonary venous drainage: the clinical value of cardiac magnetic resonance imaging,”1 Dr Tan and colleagues present elegant magnetic resonance images from a patient with total anomalous right pulmonary venous drainage into the inferior vena cava (Scimitar syndrome). Their article demonstrates the superb graphic capability of MRI and also provides evidence of the hemodynamic or functional value of magnetic resonance flow mapping in quantitating the magnitude of a left-to-right shunt. The authors’ addition of “occult” to their title, however, implies that high-tech MRI was critical to the diagnosis. I question the occult nature of this anomaly. Given that the ratio of pulmonary blood to systolic blood flow was 2.7:1, one would anticipate highly suggestive bedside findings such as a palpable lift over the right ventricle, a pulmonary ejection murmur, a persistently split second sound, and even a tricuspid inflow rumble. The contrast-enhanced magnetic resonance pulmonary venous angiogram (Figure 3 in Tan et al)1 suggests that this “scimitar” might even have been visible on plain chest radiography. Further, transthoracic and transesophageal echocardiography, which were performed before MRI, seem to have replaced, rather than augmented, the physical examination. At right-heart catheterization, a left-to-right shunt was identified at the right atrial level. The careful collection of a series of blood samples to document oxygen saturation from the superior vena cava to the inferior vena cava would have pinpointed the location of the shunt to the high inferior vena cava. Moreover, manipulation of the catheter would have permitted entry into the common vein draining the right upper and lower pulmonary veins. There, an injection of contrast medium would have illuminated the “occult.” Undeniably, MRI and other technical advances of the recent past have added immeasurably to our diagnostic and therapeutic acumen. It is not correct, however, to create the impression that MRI was, in this case, required to bring light out of darkness. The proper performance of a right-heart catheterization in searching for a shunt, a skill best appreciated nowadays by our pediatric cardiology colleagues, still needs to be taught to our adult cardiology trainees if we are to expect them to recognize conditions that might otherwise be considered occult. In this time of escalating medical costs, we have an obligation to use all of our resources with care and reason.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Inhibitory Effect of E. coli Nissle 1917 on Clinical and Standard Strains of Pseudomonas aeruginosa

Background and purpose: Pseudomonas aeruginosa is an indispensable pathogenic agent that can lead to serious infections. Antibiotic resistance is really common among bacteria, so, new therapeutic agents could be of great help in overcoming this problem. Based on previous studies, probiotic strains have a protective effect against pathogenic or Image result for opportunist bacteria opportunistic...

متن کامل

Time of Flight Technology for Gesture Interaction

In this paper we present Visteon’s findings in the field of time-of-flight (ToF) gesture interaction. We give a brief overview of current technologies before introducing our advanced technology development, which was integrated into a drivable vehicle. A significant number of hand gestures were implemented through our proprietary software and can be tested in the vehicle. We conclude this paper...

متن کامل

P-155: Outcome of Assisted Reproductive Technology in Women Aged 40 Years and Older

Background: Human fertility has been declined all over the world. Advanced women’s age is one of the most important factors in determining the success of reproduction and ageing has negative impact on ART outcome and advanced female age decreases the chance of live birth rates achieved using ART, especially after 40 years of age. The purpose of this study was to evaluate ART outcomes regarding ...

متن کامل

Response to neoadjuvant chemotherapy in locally advanced gastric and gastroesophageal cancer: Phase II clinical trial

Background: Gastric cancer is an important health problem across the world. Chemotherapy in combination with local treatment is standard treatment for locally advanced gastroesophageal cancers. The purpose of this investigation was evaluation of response and tolerability to neoadjuvant EOX regimen in locoregionally advanced gastric cancer. Materials and Methods: patients with locoregionally adv...

متن کامل

Artemether effect and its interaction with vincristine and doxorubicin on human breast carcinoma MCF-7 cells

Introduction: For thousands of years, plants have been used as the main source of drug worldwide. Recently, it has been found out that the plant Artemisia annua and especially its derivatives such as artemether have anticancer properties. Methods: In this study, the anticancer effect of artemether on MCF-7 breast cancer cell line was examined. MTT assay was used to assess the viability of c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Circulation

دوره 106 5  شماره 

صفحات  -

تاریخ انتشار 2002